PhiTools References

The PhiTools software package is used in various scientific areas from experimental to pharmacological pre-clinical and clinical applications. An important list of peer-reviewed articles has already been published in international scientific journals, books or congress abstracts. Several additional works are in progress.


topInternational journal articles

  1. de Feijter M, Katimertzoglou A, Tiemensma J, Ikram M, Luik AI Psychoneuroendocrinology 141:105749 (2022)
    Polysomnography-estimated sleep and the negative feedback loop of the hypothalamic-pituitary-adrenal (HPA) axis.
  2. D'Rozario A L, Hoyos C M, Wong K KH, Unger G, Kim J W, Vakulin A, Kao C H, Naismith S L, Bartlett D J, Grunstein R R Sleep 45(6):e1719-e1726 (2022)
    Improvements in cognitive function and quantitative sleep electroencephalogram in obstructive sleep apnea after six months of continuous positive airway pressure treatment
  3. Gnoni V, Drakatos P, Higgins S E, Duncan I, Wasserman D, Kabiljo R, Mutti C, Halasz P, Goadsby P, Leschziner G D, Rosenzweig I J. Sleep Res. 30(6):e13350 (2022)
    Cyclic alternating pattern in obstructive sleep apnea: A preliminary study.
  4. Pamidi S, Chapotot F, Wroblewski K,Whitmore H, Polomsly T, Tasali E. Am J Resp Crit Care Med. 9:e016871 (2020)
    CPAP treatment of sleep apnea reduces resting heart rate in prediabetes: a randomized placebo-controlled study.
  5. Mullins AE, Kim JW, Wong KKH, Bartlett DJ, Vakulin A, Dijk DJ, Marshall NS, Grunstein RR, D’Rozario AL. Sleep and Breathing. 4-11 (2020)
    Sleep EEG microstructure is associated with neurobehavioural impairment after extended wakefulness in obstructive sleep apnea.
  6. Lysen TS, Zonneveld HI, Muetzel RL, Ikram MA, Luik AI, Vernooij MW, Tiemeier H J. Sleep Res. e12999:1-10 (2020)
    Sleep and resting‐state functional magnetic resonance imaging connectivity in middle‐aged adults and the elderly: A population‐based study.
  7. Perrault AA, Khani A, Quairiaux C, Kompotis K, Franken P, Muhlethaler M, Schwartz S, Bayer L. Cur. Biol. 29(3):402-411 (2019)
    Whole-night continuous rocking entrains spontaneous neural oscillations with benefits for sleep and memory.
  8. Prayag A, Münch M, Aeschbach D, Chellappa S, Gronfier C. Front. Neurosci. 13:1–16 (2019)
    Dynamics of non-visual responses in humans: as fast as lightning?
  9. Prayag AS, Jost S, Avouac P, Dumortier D, Gronfier C. Clocks and Sleep. 1(1):193–208 (2019)
    Light Modulation of Human Clocks, Wake, and Sleep.
  10. Koolhaas CM, Kocevska D, te Lindert BHW, Erler NS, Franco OH, Luik AI, Tiemeier H. Sleep Med. 57:43–50 (2019)
    Objectively measured sleep and body mass index: a prospective bidirectional study in middle-aged and older adults.
  11. Buguet A, Gati Ouonkoye R, Bogui P, Cespuglio R. Rev. Neurol. 175(10):581–592 (2019)
    Geoclimatology and sleep in Africa: A mini-review.
  12. Vargas I, Vgontzas AN, Abelson JL, Faghih RT, Morales KH, Perlis ML. Sleep Med. Rev. 41:234–243 (2018)
    Altered ultradian cortisol rhythmicity as a potential neurobiologic substrate for chronic insomnia.
  13. Westerberg CE, Hawkins CA, Rendon L. Learn. Mem. 25(2):105–108 (2018)
    Sleep-dependent reductions in reality-monitoring errors arise from more conservative decision criteria.
  14. O'Reilly C, Chapotot F, Pittau F, Mella N, Picard F. J. Sleep Res. e12800:1-8 (2018)
    Nicotine increases sleep spindle activity.
  15. Morselli LL, Gamazon ER, Tasali E, Cox NJ, Van Cauter E, Davis LK. Diabetes. 67(1):155-164 (2018)
    Shared genetic control of brain activity during sleep and insulin secretion: A laboratory-based family study.
  16. Morselli LL, Temple KA, Leproult R, Ehrmann DA, Van Caute E, Mokhlesi B. Frontiers in Endocrinology. 9(377):1-12 (2018)
    Determinants of slow-wave activity in overweight and obese adults: roles of sex, obstructive sleep apnea and testosterone Levels.
  17. Borragán G, Gilson M, Atas A, Slama H, Lysandropoulos A, De Schepper M, Peigneux P. Front. Hum. Neurosci. 12:1–12 (2018)
    Cognitive fatigue, sleep and cortical activity in multiple sclerosis disease. a behavioral, polysomnographic and functional near-infrared spectroscopy investigation.
  18. Luca G, Bandarabadi M, Konofal E, Lecendreux M, Ferrie L, Figadere B, Tafti M. Front. Neurosci. 12(519):1-8 (2018)
    Lauflumide (NLS-4) is a new potent wake promoting compound.
  19. Haba-Rubio J, Marti-Soler H, Tobback N, Andries D, Marques-Vidal P, Waeber G, Vollenweider P, von Gunten A, Preisig M, Castelao E, Tafti M, Heinzer R, Popp J. Neurology. 88(5):463-469 (2017)
    Sleep characteristics and cognitive impairment in the general population: The HypnoLaus study.
  20. Kay DB, Karim HT, Soehner AM, Hasler BP, James JA, Germain A, Hall MH, Franzen PL, Price JC, Nofzinger EA, Buysse DJ. Sleep. 40(11):1-11 (2017)
    Subjective-objective sleep discrepancy is associated with alterations in regional glucose metabolism in patients with insomnia and good sleeper controls.
  21. D'Rozario AL, Cross NE, Vakulin A, Bartlett DJ, Keith KH, Wong DW, Grunstein RR. Sleep Med. Rev. 36:29–42 (2017)
    Quantitative Electroencephalogram Measures in Adult Obstructive Sleep Apnea - Potential Biomarkers of Neurobehavioural Functioning.
  22. Guyon A, Morselli LL, Balbo ML, Tasali E, Leproult R, L'Hermite-Baleriaux M, Van Cauter E, Spiegel K. Sleep. 40(6):- (2017)
    Effects of insufficient sleep on pituitary-adrenocortical response to CRH stimulation in healthy men.
  23. Ikram MA, Brusselle GGO, Murad SD, van Duijn CM, Franco OH, Goedegebure A, et al. Eur. J. Epidemiol. 32(9):807-850 (2017)
    The Rotterdam study: 2018 update on objectives, design and main results.
  24. Bat-Pitaut F, Sesso G, Deruelle C, Flori S, Porcher-Guinet V, Stagnara C, et al. Sleep Med. 30:195-203 (2017)
    Altered sleep architecture during the first months of life in infants born to depressed mothers.
  25. Walsh C M, Ruoff L, Walker K, Emery A, Varbel J, Karageorgiou E, Mance I, Heuer H W, Boxer A L, Grinberg L T, Kramer J H, Miller B L, Neylan T C. Sleep 40(11):- (2017)
    Sleepless night and day, the plight of progressive supranuclear palsy.
  26. Buguet A, Bogui P, Picot S, Cespuglio R. Neurol. Sci. 376:44-48 (2017)
    Sleep patterns in villagers and urban African volunteers in a humid tropical climate: Influence of accessibility to electric light?
  27. Najjar RP, Zeitzer JM. J. Clin. Invest. 126(3):938–947 (2016)
    Temporal integration of light flashes by the human circadian system.
  28. Zeitzer JM, Nouriani B, Rissling MB, Sledge GW, Kaplan KA, Aasly L, Palesh O, Jo B, Neri E, Dhabhar FS, Spiegel D. Breast Cancer Research and Treatment 158(1):43-50 (2016)
    Aberrant nocturnal cortisol and disease progression in women with breast cancer.
  29. McBean AL, Najjar RP, Schuchard RA, Hall CD, Wang C-A, Ku B, Zeitzer JM. J. Clin. Sleep Med. 12(11):1477-1486 (2016)
    Standing balance and spatiotemporal aspects of gait are impaired upon nocturnal awakening in healthy late middle-aged and older adults.
  30. Seeley CJ, Smith CT, MacDonald KJ, Beninger RJ. Behav. Neurosci. 130(3):271-280 (2016)
    Ventromedial prefrontal theta activity during rapid eye movement sleep is associated with improved decision-making on the Iowa gambling task.
  31. Grimaldi D, Carter JR, Van Cauter E, Leproult R. Hypertension. 68(1):243-50 (2016)
    Adverse impact of sleep restriction and circadian misalignment on autonomic function in healthy young adults: novelty and significance.
  32. Nader RS, Murkar AL, Smith CT. Front. Psychol. 7(1555):1-7 (2016)
    Sleep changes in adolescents following procedural task training.
  33. Zuurbier LA, Vernooij MW, Luik AI, Kocevska D, Hofman A, Whitmore H, et al. Neurobiol. Sleep Circadian Rhythm. 1(1):1-7 (2016)
    Apnea-hypopnea index, nocturnal arousals, oxygen desaturation and structural brain changes: A population-based study.
  34. Kay DB, Karim HT, Soehner AM, Hasler B, Wilckens KA, James JA, Aizenstein HJ, Price JC, Rosario BL, Kupfer D, Germain A, Hall MH, Franzen PL, Nofzinger EA, Buysse DJ. Sleep. 39191(10):1779-1794 (2016)
    Sleep-Wake Differences in Relative Regional Cerebral Metabolic Rate for Glucose Among Patients With Insomnia Compared With Good Sleepers.
  35. Leproult R, Deliens G, Gilson M, Peigneux P. Sleep. 38(5):707-715 (2015)
    Beneficial impact of sleep extension on fasting insulin sensitivity in adults with habitual sleep restriction.
  36. Broussard JL, Chapotot F, Abraham V, Day A, Delebecque F, Whitmore HR, Tasali E. Diabetologica. 58(4):791-798 (2015)
    Sleep restriction increase free fatty acids in healthy men.
  37. Pigeon WR, Heffner KL, Crean H, Gallegos AM, Walsh P, Seehuus M, Cerulli C. Contemp. Clin. Trials 45(B):252-260 (2015)
    Responding to the need for sleep among survivors of interpersonal violence: A randomized controlled trial of a cognitive–behavioral insomnia intervention followed by PTSD treatment.
  38. Neu D, Maitresse O, Newell J, Verbanck P, Peigneux P, Deliens G. Clin. Neurophysiol. 45(2):167-175 (2015)
    Does more sleep matter? Differential effects of NREM- and REM-dominant sleep on sleepiness and vigilance.
  39. Haba-Rubio J, Marques-Vidal P, Tobback N, Andries D, Preisig M, Kuehner C, Vollenweider P, Waeber G, Luca G, Tafti M, Heinzer R. Sleep Med. 16(11):1321-1326 (2015)
    Bad sleep? Don't blame the moon! A population-based study.
  40. Luca G, Haba-Rubio J, Andries D, Tobback N, Vollenweider P, Waeber G, et al. Ann. Med. 47(6):1-10 (2015)
    Age and gender variations of sleep in subjects without sleep disorders.
  41. Westerber CE, Florczak SM, Weintraub S, Mesulam MM, Marshall L, Zee PC, Paller KA. Neurobiol. Aging 36(9):2577-2586 (2015)
    Memory improvement via slow-oscillatory stimulation during sleep in older adults.
  42. Galer S, Urbain C, De Tiège X, Emeriau M, Leproult R, Deliens G, et al. Epilepsy Behav. 43(1):16-23 (2015)
    Impaired sleep-related consolidation of declarative memories in idiopathic focal epilepsies of childhood.
  43. Pisani MA, Friese RS, Gehlbach BK, Schwab RJ, Weinhouse GL, Jones SF. Am. J. Respir. Crit. Care Med. 191(7):731-8 (2015)
    Sleep in the intensive care unit.
  44. Hofman A, Brusselle GGO, Murad SD, van Duijn CM, Franco OH, Goedegebure A, et al. Eur. J. Epidemiol. 30(8):661-708 (2015)
    The Rotterdam study: 2016 objectives and design update.
  45. Gilson M, Deliens G, Leproult R, Bodart A, Nonclercq A, Ercek R, et al. Brain Sci. 6(1):1 (2015)
    Enriched naps are associated with memory consolidation for sad stories and enhance mood-related reactivity.
  46. Moore HE, Mignot E. Comput. Methods Biomech. Biomed. Eng. Imaging Vis. 3(3):123-35 (2015)
    SEV - a software toolbox for large scale analysis and visualization of polysomnography data.
  47. Nader RS, Smith CT. Front. Hum. Neurosci. 9(February):1-8 (2015)
    Correlations between adolescent processing speed and specific spindle frequencies.
  48. Luik AI, Noteboom J, Zuurbier LA, Whitmore H, Hofman A, Tiemeier H. Sleep Health. 1(2):128-132 (2015)
    Sleep apnea severity and depressive symptoms in a population-based study.
  49. Luik AI, Zuurbier LA, Whitmore H, Hofman A, Tiemeier H. J. Sleep Res. 24(3):305-308 (2015)
    REM sleep and depressive symptoms in a population-based study of middle-aged and elderly persons.
  50. Ward MP, Peters KR, Smith CT. Exp. Brain Res. 232(5):1525-1534 (2014)
    Effect of emotional and neutral declarative memory consolidation on sleep architecture.
  51. Zeitzer JM, Fisicaro RA, Ruby NF, Heller CH. J. Biol. Rhythms. 29(5):370–376 (2014)
    Millisecond flashes of light phase delay the human circadian clock during sleep.
  52. Deliens G, Peigneux P. Cogn. Emot. 28(1):698-706 (2014)
    One night of sleep is insufficient to achieve sleep-to-forget emotional decontextualisation processes.
  53. Tasali E, Chapotot F, Wroblewski K, Schoeller DA. Appetite. 80:220-224 (2014)
    The effects of extended bedtimes on sleep duration and food desire in overweight young adults: A home-based intervention.
  54. Peters KR, Ray LB, Fogel SM, Smith V, Smith CT. PLoS One. 9(3):e91047 (2014)
    Age differences in the variability and distribution of sleep spindle and rapid eye movement densities.
  55. Cervena K, Espa F, Perogamvros L, Perrig S, Merica H, Ibanez V. Clin. Neurophysiol. 125(5):979-87 (2014)
    Spectral analysis of the sleep onset period in primary insomnia.
  56. Deliens G, Neu D, Peigneux P. J. Sleep Res. 22:656-62 (2013)
    Rapid eye movement sleep does not seem to unbind memories from their emotional context.
  57. Moore HE. Comput. Methods Biomech. Biomed. Eng. Imaging Vis. 1(4):225-33 (2013)
    Visualization of EEG activity for stimulating sleep research.
  58. Morselli LL, Nedeltcheva A, Leproult R, Spiegel K, Martino E, Legros J-J, et al. Eur. J. Endocrinol. 168:763-70 (2013)
    Impact of GH replacement therapy on sleep in adult patients with GH deficiency of pituitary origin.
  59. Deliens G, Leproult R, Neu D, Peigneux P. Sleep. 36(12):1875-83 (2013)
    Rapid eye movement and non-rapid eye movement sleep contributions in memory consolidation and resistance to retroactive interference for verbal material.
  60. Watson PL, Pandharipande P, Gehlbach BK, Thompson JL, Shintani AK, Dittus BS, et al. Crit. Care. Med. 41(8):1958-67 (2013)
    Atypical sleep in ventilated patients: empirical electroencephalography findings and the path toward revised ICU sleep scoring criteria.
  61. Caufriez A, Leproult R, L’Hermite-Balériaux M, Kerkhofs M, Copinschi G. Clin. Endocrinol. (Oxf). 79(5) (2013)
    Effects of a 3-week dehydroepiandrosterone administration on sleep, sex steroids and multiple 24-h hormonal profiles in postmenopausal women: a pilot study.
  62. Bergstrom RA, Choi JH, Manduca A, Shin H-S, Worrell GA, Howe CL. Sci Rep. 3:1483 (2013).
    Automated identification of multiple seizure-related and interictal epileptiform event types in the EEG of mice.
  63. Colas D, Chuluun B, Warrier D, Blank M, Wetmore DZ, Buckmaster P, et al. Br. J. Pharmacol. 169(5):963-73 (2013)
    Short-term treatment with the GABAA receptor antagonist pentylenetetrazole produces a sustained pro-cognitive benefit in a mouse model of Down’s syndrome.
  64. Buguet A, Chapotot F, Ngampo S, Bouteille B, Cespuglio R. Future Neurology. 7(4):453-472 (2012).
    Management of African trypanosomiasis of the CNS: polysomnography as a noninvasive staging tool.
  65. Picot A, Whitmore H, Chapotot F. IEEE Trans. Biomed. Eng. 59(10):2808-2817 (2012).
    Detection of cortical slow waves in the sleep EEG using a modified matching pursuit method with a restricted dictionary.
  66. Vienne J, Lecciso G, Constantinescu I, Schwartz S, Franken P, Heinzer R, Tafti M. Sleep. 35(8):1071-83 (2012).
    Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory.
  67. Westerberg CE, Mander BA, Florczak SM, Weintraub S, Mesulam MM, Zee PC, Paller KA. J. Int. Neuropsychol. Soc. 3:1-11 (2012).
    Concurrent impairments in sleep and memory in amnestic mild cognitive impairment.
  68. Salih DAM, Rashid AJ, Colas D, de la Torre-Ubieta L, Zhu RP, Morgan AA, Santo EE, Ucar D, Devarajan K, Cole CJ, Madison DV, Shamloo M, Butte AJ, Bonni A, Josselyn SA, Brunet A.Genes and Development. 26(24):2780-2801 (2012)
    FoxO6 regulates memory consolidation and synaptic function.
  69. Gehlbach BK, Chapotot F, Leproult R, Whitmore H, Poston J, Pohlman M, Miller A, Pohlman AS, Nedeltcheva A, Jacobsen JH, Hall JB, Van Cauter E.Sleep. 35(8):1105-1114 (2012).
    Temporal disorganization of circadian rhythmicity and sleep-Wake regulation in mechanically ventilated patients receiving continuous intravenous sedation.
  70. Drouet JB, Rousset C, Maury R, Michel V, Buguet A, Cespuglio R, Canini F. Eur. J. Pharmacol. 6(7):e22078 (2011).
    Single administration of metyrapone modifies sleep-wake patterns in the rat.
  71. Caufriez A, Leproult R, L'Hermite-Baleriaux M, Kerkhofs M, Copinschi G. J. Clin. Endocrinol. Metab. 96(4):614-23 (2011).
    Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women.
  72. Fogel SM, Smith CT, Higginson CD, Beninger RJ. Physiol. Behav. 102(2):170-174 (2011).
    Different types of avoidance behavior in rats produce dissociable post-training changes in sleep.
  73. Mpandzou G, Cespuglio R, Ngampo S, Bandzouzi B, Bouteille B, Vincendeau P, Buguet A. J. Neurol. Sci. 305(1-2):112-5 (2011).
    Polysomnography as a diagnosis and post-treatment follow-up tool in human African trypanosomiasis: a case study in an infant.
  74. Zeitzer JM, Ruby NF, Fisicaro RA, Heller HC. PLoS One. 6(7):e22078 (2011).
    Response of the human circadian system to millisecond flashes of light.
  75. Tasali E, Chapotot F, Leproult R, Whitmore H, Ehrmann DA. J. Clin. Endocrinol. Metab. 96(2):365-74. (2011).
    Treatment of obstructive sleep apnea improves cardiometabolic function in young obese women with polycystic ovary syndrome.
  76. Picot A, Whitmore H, Chapotot F. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2011:4824-7 (2011).
    Automated detection of sleep EEG slow waves based on matching pursuit using a restricted dictionary.
  77. Smith CT. Sleep Medicine Clinics. 6(1):59-70 (2011).
    Sleep states and memory processing in rodents: a review.
  78. Fogel SM, Smith CT. Neurosci. Biobehav. Rev. 35(5):1154-1165 (2011).
    Different types of avoidance behavior in rats produce dissociable post-training changes in sleep.
  79. Zeitzer JM, Fisicaro RA, Grove ME, Mignot E, Yesavage JA, Friedman L. Psychiat. Res. 652(1-3):60-4 (2011).
    Faster REM sleep EEG and worse restedness in older insomniacs with HLA DQB1*0602.
  80. Bayer L, Constantinescu I, Perrig S, Vienne J, Vidal PP, Mühlethaler M, Schwartz S. Cur. Biol. 21(12):R461–R462. (2011).
    Rocking synchronizes brain waves during a short nap.
  81. Zoubek L, Chapotot F. Comm. Comput. Inform. Sci. 188:106-117 (2011).
    Automatic classification of sleep/wake stages using two-step system.
  82. Merica H, Fortune RD. PLoS One. 6(8):e23593 (2011).
    The neuronal transition probability (NTP) model for the dynamic progression of non-REM sleep EEG: The role of the suprachiasmatic nucleus.
  83. Charbonnier S, Zoubek L, Lesecq S, Chapotot F. Comp. Biol. Med. 41(6):380-389 (2011).
    Self-evaluated automatic classifier as a decision-support tool for sleep/wake staging.
  84. Tasali E, Chapotot F, Leproult R, Whitmore H, Ehrmann D. J. Clin. Endocrinol. Metab. 96(2):365-74 (2011).
    Treatment of obstructive sleep apnea improves cardiometabolic function in young obese women with polycystic ovary syndrome.
  85. Mander BA, Reid K, Baron KG, Tjoa T, Parrish TB, Paller KA, Gitelman DR, Zee PC. J. Neurosci. 30(7):2686-2693 (2010).
    EEG measures index neural and cognitive recovery from sleep deprivation.
  86. Sforza E, Marcoz JP, Foletti G. Epileptic Disord. 12(3):228-31 (2010).
    Sleep spindle activity in double cortex syndrome: a case report.
  87. Trousselard M, Cian C, Roux A, Ferhani O, Barraud P, Baert P. Medecine et Armees. 38(4):299-310 (2010).
    Conséquences psycho-cognitives et physiologiques d’un exercice d’évacuation d’un sous-marin en plongée.
  88. Copinschi G, Nedeltcheva A, Leproult R, Morselli LL, Spiegel K, Martino E, Legros JJ, Weiss RE, Mockel J, Van Cauter E. J. Clin. Endocrinol. Metab. 95(5):2195-202 (2010).
    Sleep disturbances, daytime sleepiness, and quality of life in adults with growth hormone deficiency.
  89. Ray L, Fogel S, Smith C, Peters KR. J. Sleep Res. 19(2):374-8 (2010).
    Validating an automated sleep spindle detection algorithm using an individualized approach.
  90. Fogel SM, Smith CT, Beninger RJ. Brain Res. 1319:112-117 (2010).
    Too much of a good thing? Elevated baseline sleep spindles predict poor avoidance performance in rats.
  91. Fogel SM, Smith CT, Beninger RJ. Behav Neurosci. 124(1):79-86 (2010).
    Increased GABAergic activity in the region of the pedunculopontine and deep mesencephalic reticular nuclei reduces REM sleep and impairs learning in rats.
  92. Chapotot F, Becq G. Int. J. Adapt. Contr. Signal Process. 24(5):409-423 (2010).
    Automated sleep-wake staging combining robust feature extraction, artificial neural network classification, and flexible decision rules.
  93. Fogel SM, Smith CT, Beninger RJ. Brain Res. Bull. 79(6):445-451 (2009).
    Evidence for 2-stage models of sleep and memory: Learning-dependent changes in spindles and theta in rats.
  94. Trousselard M, Cian C, Barraud PA, Ferhani O, Roux A, Claverie D, Canini F, Baert P. Aviat. Space Environ. Med. 80(10):850-6 (2009).
    Physiological and psychological effects of escape from a sunken submarine on shore and at sea.
  95. Bucolo M, Di Grazia F, Fortuna L, Frasca M, Sapuppo F. Math. Biosci. Eng. 5(20:261-276 (2008).
    An environment for complex behaviour detection in bio-potential experiments.
  96. Paradiso R, Bourdon L, Loriga G. Adv. Sci. Tech. 60:101-110 (2008).
    Smart Sensing Uniforms for Emergency Operators.
  97. Sforza E, Chapotot F, Pigeau R, Buguet A. Clin. Neurophysiol. 119:1590-11599 (2008).
    Time of night and first night effects on arousal response in healthy adults.
  98. Dauvilliers Y, Bisser S, Chapotot F, Vatunga G, Cespuglio R, Josenando T, Buguet A. Sleep 31(3):348-354 (2008).
    Hypocretin and Human African Trypanosomiasis.
  99. Tasali E, Leproult R, Ehrmann DA, Van Cauter E. Proc. Natl. Acad. Sci. USA Jan 2 (2008).
    Slow-wave sleep and the risk of type 2 diabetes in humans.
  100. Peters KR, Ray LB, Smith V, Smith CT. J. Sleep Res. 17(1):23-33 (2008).
    Changes in the density of stage 2 sleep spindles following motor learning in young and older adults.
  101. Zoubek L, Charbonnier S, Lesecq S, Buguet A, Chapotot F. Biomed. Signal Process. Control 2:171-179 (2007).
    Feature selection for sleep/wake stages classification using data driven methods.
  102. Buguet A. J. Neurol. Sci. 262(1–2):145-152 (2007).
    Sleep under extreme environments: Effects of heat and cold exposure, altitude, hyperbaric pressure and microgravity in space.
  103. Sloan EP, Maunder RG, Hunter JJ, Moldofsky H. Biopsychosoc. Med. 1:20 (2007).
    Insecure attachment is associated with the alpha-EEG anomaly during sleep.
  104. Quera Salva MA, Vanier B, Laredo J, Hartley S, Chapotot F, Moulin C, Lofaso F, Guilleminault C. Int. J. Neuropsychopharmacol. 10(5):691-6 (2007).
    Major depressive disorder, sleep EEG and agomelatine: an open-label study.
  105. Latta F, Leproult R, Tasali E, Hofmann E, Van Cauter E. Sleep 28(12):1525-34 (2005).
    Sex differences in delta and alpha EEG activities in healthy older adults.
  106. Merica H, Fortune RD. Cereb. Cortex 15(7):877-84 (2005).
    Spectral power time-courses of human sleep EEG reveal a striking discontinuity at ~18Hz marking division between NREM-specific and wake/REM-specific fast frequency activity.
  107. Buguet A, Bisser S, Losenando T, Chapotot F, Cespuglio R. Acta Trop. 93(1):107-17 (2005).
    Sleep structure: a new diagnostic tool for stage determination in sleeping sickness.
  108. Bourdon L, Coli S, Loriga G, Taccini N, Gros B, Gemignani A, Cianflone D, Chapotot F, Dittmar A, Paradiso R. Comput. Cardiol. 32:615-18 (2005).
    First Results with the Wealthy Garment ElectroCardiogram Monitoring System.
  109. Darsaud A, Bourdon L, Mercier S, Chapotot F, Bouteille B, Cespuglio R, Buguet A. Sleep 27(1):42-6 (2004).
    Twenty-four hour disruption of the sleep-wake cycle and sleep-onset REM-like episodes in a rat model of African trypanosomiasis.
  110. Cervena K, Dauvilliers Y, Espa F, Touchon J, Matousek M, Billiard M, Besset A. J. Sleep Res. 13:385-93 (2004).
    Effect of cognitive behavioural therapy for insomnia on sleep architecture and sleep EEG power spectra in psychophysiological insomnia.
  111. Merica H, Fortune RD. Sleep Med. Rev. 8(6):473-85 (2004).
    State transitions between wake and sleep, and within the ultradian cycle, with focus on the link to neuronal activity.
  112. Sforza E, Chapotot F, Lavoie S, Roche F, Pigeau R, Buguet A. Clin. Neurophysiol. 115(11):2242-5 (2004).
    Heart rate activation during spontaneaous arousals from sleep: effect of sleep deprivation.
  113. Sforza E, Chapotot F, Pigeau R, Naitoh P, Buguet A. Sleep 27(6):1068-75 (2004).
    Effects of sleep deprivation on spontaneaous arousals in humans.
  114. Esposito MJ, Zamboni G, Natale V, Lucidi F, Devoto A, Violani C. Neurosci. Lett. 368(1):52-56 (2004).
    Single and sequential REM sleep episodes in humans: a phylogenetic left-over?.
  115. Lavoie S, De Bilbao F, Haba-Rubio J, Ibanez V, Sforza E. Clin. Neurophysiol. 115(10):2236-2246 (2004).
    Influence of sleep stage and wakefulness on spectral EEG activity and heart rate variations around periodic leg movements.
  116. Roky R, Chapotot F, Taoudi-Benchekroun M, Hakkou F, Elkhalifi H, Benaji B, Buguet A. J. Sleep Res. 12(2):95-101 (2003).
    Daytime sleepiness during Ramadan intermittent fasting: polysomnographic and quantitative waking EEG study.
  117. Leproult R, Colecchia E, Berardi Am, Stickgold R, Kosslyn Sm, Van Cauter E. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284(2):R280-90 (2003).
    Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated.
  118. Merica H, Fortune RD. Cereb. Cortex13:1044_50 (2003).
    A unique pattern of sleep structure is found to be identical at all cortical sites: a neurobiological interpretation.
  119. Chapotot F, Pigeau R, Canini F, Bourdon L, Buguet A. Psychopharmacol. (Berl) 166(2):127-138 (2003).
    Distinctive effects of modafinil and d-amphetamine on the homeostatic and circadian modulation of the human waking EEG.
  120. Sforza E, Jouny C, Ibanez V. Clin. Neurophysiol. 113(6):883-91 (2003).
    Time-dependent variation in cerebral and autonomic activity during periodic leg movements in sleep: implications for arousal mechanisms.
  121. Buguet A, Bouteille B, Cespuglio R, Bisser S, Chapotot F, Bourdon L, Vincendeau M, Radomski MW, Dumas M. Med. Trop. 63(3):1-5 (2003).
    Icon PDF La maladie du sommeil: la recherche oubliee.
  122. Sforza E, Grandin S, Jouny C, Rochat T, Ibanez V. Eur. Respir. J. 19:645-652 (2002).
    Is waking electroencephalographic activity a predictor of daytime sleepiness in sleep-related Breathing disorders?
  123. Roky R, Chapotot F, Hakkou F, Benchekroun M, Buguet A. J. Sleep Res. 10(4):319-327 (2001).
    Sleep during Ramadan intermittent fasting.
  124. Buguet A, Bourdon L, Bisser S, Chapotot F, Radomski MW, Dumas M. Med. Trop. 61(4-5):328-339 (2001).
    Icon PDF La maladie du sommeil: trouble majeur des rythmes circadiens.
  125. Chapotot F, Buguet A, Gronfier C, Brandenberger G. Neuroendocrinology 73(5):312-321 (2001).
    HPA axis activity is related to the level of central arousal: effect of sleep deprivation on the association of high frequency waking EEG with cortisol release.
  126. Gaudreau H, Morettini J, Lavoie HB, Carrier J. Neurobiol. Aging 22(3):461-8 (2001).
    Effects of a 25-h sleep deprivation on daytime sleep in the middle-aged.
  127. Chapotot F, Jouny C, Buguet A, Brandenberger G. Neuroreport 11(10):2223-2227 (2000).
    High frequency waking EEG: reflection of a slow ultradian rhythm in arousal.
  128. Sforza E,Jouny C, Ibanez I. Clin. Neurophysiol. 111:1611-1619 (2000).
    Cardiac activation during arousal in humans: further evidence for hierarchy in the arousal response.
  129. Jouny C, Chapotot F, Merica H. Neuroreport 11(17):3667-3671 (2000).
    EEG spectral activity during paradoxical sleep: further evidence for cognitive processing.
  130. Chapotot F, Gronfier C, Jouny C, Muzet A, Brandenberger G. J. Clin. Endocrinol. Metab. 83(12):4263-4268 (1998). Pharmacia & Upjohn Award.
    Cortisol secretion is related to electro-encephalographic alertness in human subjects during daytime wakefulness.

topBooks, and Congress abstracts

  1. Pamidi S, Chapotot F, Wroblewski K, Khalyfa A, Stepien S, Sharif-Sidi K, Tremblay G, Whitmore H, Tasali E.American Thoracic Society A19:A1044 (2018).
    All-night CPAP treatment reduces 24-hour resting heart rate in prediabetes: a randomized placebo-controlled study.
  2. Nader R, Smith C, Sabbagh MA. Sleep 35(Suppl):A21 (2012).
    Evidence of a superfast spindle in the 16-19Hz frequency range.
  3. Smith C, Nader R, Murkar A, Sabbagh MA. Sleep 35(Suppl):A22 (2012).
    Spindle density varies with age among three spindle types (11-13.5Hz, 13.5-16Hz, 16-18.5Hz).
  4. Nader R, Smith C, Murkar A, Sabbagh MA. Sleep 35(Suppl):A22 (2012).
    Spindle duration varies among three spindle types and with age.
  5. Smith C, Nader R, Murkar A, Sabbagh MA. Sleep 35(Suppl):A22 (2012).
    Spindle amplitude varies with age among three spindle types (11-13.5Hz, 13.5-16Hz, 16-18.5Hz).
  6. Mander BA, Zhu A, Lu BS, Saletin JM, Ancoli-Israel S, Jagust WJ, Walker M. Sleep 35(Suppl):A23 (2012).
    Age-related impairments of memory and fast sleep spindles are mediated by deterioration of cortico-thalamic white matter pathways.
  7. Picot A, Whitmore H, Chapotot FSleep 35(Suppl):A131 (2012).
    Automated knowledge-based detection of cortical slow waves in sleep EEG using matching pursuit.
  8. McGee-Koch LL, Malkani R, Reid KJ, Chapotot F, Whitmore H, Zee P. Sleep 35(Suppl):A278 (2012).
    The temporal distribution of slow wave activity during sleep is an objective marker of subjective daytime sleepiness.
  9. Picot A, Whitmore H, Chapotot F. The Engineering in Medicine and Biology Conference (2011).
    Automated detection of sleep EEG slow waves based on matching pursuit using a restricted dictionary.
  10. Picot A, Van Cauter E, Chapotot F. Sleep 34(Suppl):A324 (2011).
    Validation of a novel sleep EEG slow wave automated detection algorithm.
  11. Zoubek L, Charbonnier S, Lesecq S, Buguet A, Chapotot F. Proceedings of the 17th World Congress, The International Federation of Automatic Control 5227:5232 (2008).
    Icon PDF A two-step sleep/wake stages classifier taking into account artifacts in the polysomnographic signals.
  12. Chapotot F, Zoubek L, Becq G. Sleep 31(Suppl):A328 (2008).
    Artificial neural network scoring of human sleep-wake stages combining short-epoch feature extraction and post-processing inference rules.
  13. Zoubek L, Charbonnier S, Lesecq S, Buguet A, Chapotot F. Modeling and Control in Biomedical Systems6(1):117-122 (2006).
    Knowledge extraction about sleep/wake stages using data driven methods.
  14. Buguet A, Chapotot F, Bisser S, Cespuglio R, Bouteille B. In: Sleep: a comprehensive handbook Lee-Chiong LT (Ed) Wiley, Hoboken 163-173 (2006).
    Sleeping sickness: human African trypanosomiasis.
  15. Becq G, Charbonnier S, Chapotot F, Buguet A, Bourdon L, Baconnier P. In: Softcomputing in Knowledge Discovery - Methods and Applications Halgamuge S and Wang L (Eds) Springer Verlag. 8 113-127 (2005).
    Icon PDF Comparison between five classifiers for automatic scoring of human sleep recordings.
  16. Buguet A, Bouteille B, Cespuglio R, Chapotot F. In: Les troubles du sommeil Billard M and Dauvilliers Y (Eds) Masson, Paris 309-323 (2005).
    Maladies infectieuses et sommeil.
  17. Buguet A, Bisser S, Josenando T, Chapotot F, Cespuglio R, Dumas M. Rev. Neurol. 2S:151 (2005).
    Polysomnographie: diagnostic non invasif du stade nerveux de la trypanosomose humaine africaine (THA).
  18. Cervena K, Dauvilliers Y, Espa F, Touchon J, Matousek M, Billiard M, Besset A. J. Sleep Res. 13(1):129 (2004). ESRS Sanofi-Aventis Awards.
    Effect of cognitive behavioural therapy for insomnia on sleep architecture and sleep EEG power spectra in psychophysiological insomnia.
  19. Leproult R, Tasali E, Saaresranta T, Pannain S, Miller J, Alverdy E, Van Cauter E. J. Sleep Res. 13(1):444 (2004). ESRS H Kristbjarnarson's Awards.
    Morbidly obese women have less slow wave sleep than their age and gender matched controls.
  20. Buguet A, Cespuglio R, Bisser S, Chapotot F, Josenando T, Dumas M. J. Sleep Res. 13(1):109 (2004).
    Polysomnography, a new means for human African trypanosomiasis stage diagnosis.
  21. Chevrier C, Chapotot F, Darsaud C, Cespuglio R, Buguet A, Bourdon L. J. Sleep Res. 13(1):135 (2004).
    Chronobiological alterations in sleep-wake stages and core temperature in experimental african trypanosomiasis.
  22. Quera-Salva M, Laredo J, Chapotot F, Vannier B, Bohic M, Moulin C, Morlat D, Bodinat C, Lofaso F, Guilleminault C. J. Sleep Res. 13(1):593 (2004).
    Sleep EEG during a major depression episode in patients consulting for a sleep/wake complaint.
  23. Chapotot F, Becq G, Sforza E, Buguet A. J. Sleep Res. 13(1):132(2004).
    Icon PDF Automatic sleep-wake stage scoring using artificial neural networks: optimisation and evaluation.
  24. Chapotot F, Bisser S, Panzo A, Josenando T, Buguet A. J. Sleep Res. 13(1):13 (2004).
    EEG slow-wave activity: a potential marker of the nervous phase of human African trypanosomiasis.
  25. Becq G, Charbonnier S, Chapotot F, Buguet A, Bourdon L, Baconnier P. In: Proceedings of the 1st international conference on fuzzy systems and knowledge discovery: Computational intelligence for the E-age Wang L, Halgamuge S, Yao X (Eds) Orchid Country Club (1) pp166 (2002).
    Icon PDF Comparison between five classifiers for automatic scoring of human sleep recordings.
  26. Chapotot F, Pigeau R, Naitoh P, Buguet A. Methods and Findings in Experimental and Clinical Pharmacology 24D:154 (2002). IPEG-PAREXEL Young Scientist Awards
    Distinctive effects of modafinil and d-amphetamine on the homeostatic and circadian regulation of the human waking EEG.
  27. Chapotot F, Buguet A, Brandenberger G. Stress 5:84 (2002).
    Alteration of the ultradian coupling between waking EEG arousal and HPA axis activity during sleep deprivation.
  28. Sforza E, Jouny C, Ibanez V. J. Sleep Res. 11(1):416 (2002).
    Temporal evolution of arousal response during periodic leg movements: Evidence for circadian influence.
  29. Buguet A, Tapie P, Chapotot F, Banzet S, Bogui P, Cespuglio R. J. Sleep Res. 11(1):30 (2002).
    Sleep in tropical Africa: At the laboratory in villages without electrical power.
  30. Buguet A, Tapie P, Bisser S, Chapotot F, Doua F, Cespuglio R. J. Sleep Res. 11(1):29 (2002).
    Sleep in sleeping sickness patients under ambulatory monitoring.
  31. Chapotot F, Buguet A, Brandenberger G. b>J. Sleep Res. 11(1):36 (2002).
    Sleep deprivation alters the ultradian coupling between waking EEG arousal and HPA axis activity.
  32. Chapotot F, Pigeau R, Buguet A. Actas di Fisilogia 7:254 (2001).
    Distinctive effects of Modafinil and d-amphetamine on the human EEG power spectrum during 60 uninterrupted waking hours.
  33. Darsaud A, Mercier S, Chapotot F, Bouteille B, Chevrier C, Canini F, Bourdon L, Cespuglio R, Dumas M, Buguet A. Med. Trop. 61(3):280 (2001).
    Rythmes circadiens de la vigilance dans la trypanosomose africaine: étude numérique chez le rat.
  34. Jouny C, Chapotot F, Merica H. Sleep Res. Online 2(1):47 (1999).
    REM-related EEG spectral changes during paradoxical sleep in humans.
  35. Chapotot F, Jouny C, Buguet A, Brandenberger G. Sleep Res. Online 2(1):252 (1999).
    Temporal relationships between EEG frequency bands in awake man.
  36. Chapotot F, Jouny C, Buguet A, Brandenberger G. Sleep Res. Online 2(1):176 (1999).
    Increased HPA activity during sleep deprivation in man.
  37. Chapotot F, Gronfier C, Jouny C, Muzet A, Brandenberger G. J. Sleep Res. 7(2):44 (1998).
    Cortisol secretion is temporally related to EEG beta activity during wakefulness in man.

topMultimedia

  1. Chapotot F.
    Icon PPS Methods and Tools for a quantitative study of the sleep/wake cycle.
  2. Chapotot F. Journees dediees aux applications pharmaceutiques et medicales avec l'environnement MATLAB. Sevres (2005).
    Icon PPS PRANA : Une boite à outils MATLAB pour l'analyse des enregistrements polygraphiques.
  3. Tung J, Oxenford R. MATLAB News and Notes Spring (2001).
    Analyzing data for sleep research.

PhiTools provides advanced software solutions and services for biosignal processing, sleep analysis, psychophysiological research and clinical trials. PhiTools, software tools and services for psychophysiology, polysmonography and chronobiology.